Dr. K Shankar Rao ( Professor)
Rasa Shashtra & Bhaisjya Kalpana
Paper Published in International Journals:-
Abhrak Bhasma (Biotite mica nanoparticles) Induses Cytoxicity in Adenocarcinoma Human Alveolar Basal Epithelial Cellls (A549)
Dr. Ravi Suryavanshi ( Reader)
Shalya Tantra
Paper Published in International Journals:-
1. “An Appraisal of etiopathogenesis review of Arsha vyadhi according to Ayurveda” (International jounrnalof Indian medicine IJAM ISSN: 2582-7634 Volume 2, Issue-2,March 2021)
2. ” A study on the effect of Kutajyoga with comparision to Ciprofloxacin objective parameters in patients of Mootrakrichha with special referance to cystitis .”(InInternational Journal of Research in Ayurved and Pharmacy / Volume 8, Issue 3,May-June2017/ISSN (Print) 2277-4343/ ISSN (Online) 2229-3566).
Dr. Shailesh Dhenge (Asst. Professor)
Shalya Tantra
Paper Published in International Journals:-
Role of Shallaki niryas Ksharasutra in the Management of Arsha- A Case Study
ShaileshDhenge1, PronabHaldar2, K Baslingappa3
1PhD Scholar, Department of Ayurveda (ShalyaTantra), Mandsaur University Mandsaur, Madhya Pradesh, India
2
Professor, Department of Rasashastra, Mandsaur Institute of Ayurved Education and Research &
Hospital, Mandsaur, Madhya Pradesh, India
3Associate Professor, Shalya Tantra, Govt. Ayurvedic Medical College and Hospital, Bilaspur, Chattisgar
ABSTRACT
According to 2019 ICD-10-CM Diagnosis Code K64.9 hemorrhoids are dilated veins in the lower part of the rectum or anal canal. Hemorrhoids can be internal or external, or protruding from inside to outside of the anal canal and having symptoms which include bleeding, itching, and pain. Guda (~anus) is undoubtedly a Marma (~vital points), and it is well known for its chronicity and difficult management and Arsha (~hemorrhoids) occurs in anal region. Vitiated Dosha (ailments) localizes in Gudavali (~folds), Pradhanadhamani (~vein) and Mansadhara kala (~layers) and vitiates Twak (~skin), Mansa (~muscle), Meda (~fats) and Rakta (~blood), resulting in the Annavahasrotodushti (~obstruction of digestive system). Snuhi kshira ksharsutra is considered as the standard Ksharsutra although this Ksharsutra has been a landmark success but it has certain drawbacks like pain, burning sensation and itching associated during therapy. So, through this study, we find out a safe, simple, effective treatment without any complications. Two patients were included in the study and one patient was treated with Shallaki niryas ksharasutra ligation while the other was treated with Snuhi kshira ksharsutra ligation. The study observed that Shallaki niryas ksharasutra ligation gives relief in pain and burning sensation. Reduction in discharge was also observed with Shallaki niryas ksharsutra as compared to Snuhi kshira kasharasutra. This study finally concluded that there is a need for further study on the large populations to the established result of the current study.
Key words: Arsha, Hemorrhoids, Marma
INTRODUCTION
Hemorrhoids are dilated veins within the anal canal in the sub epithelial region formed by radicals of the superior, middle and inferior rectal veins. Internal hemorrhoid means it is within the anal canal and internal to the anal orifice. It is covered with mucous membrane and it is bright red or purple in color. It usually commences at the anorectal ring and ends at the dentate line. The external hemorrhoid is situated outside the anal orifice and is covered by skin. The two varieties may coexist and the condition is called interno-external hemorrhoids. The internal variety may be first degree where the piles remain within anus and that may bleed but do not prolapse in second degree piles that prolapsed on straining during the defecation but return or recede spontaneously in the third-degree piles that prolapsed during stool passing but can be replaced by manual help or digital pressure or protruded. [1]
Sushruta samhita (800 – 1000 B.C.) Charak samhita (1000 B.C.) and Acharya Vagbhata (7 th A.D.) all of them have dedicated separate chapter to describe etiology pathogenesis symptomatology and the management of Arshas. One of the contributions during this period is application of Ksharsutra described by Chakrapani (11 th A.D.) In his Chakradutta in the context of Arshobhagandar chikitsa. [2] Ayurveda classified different types of Arsha including Vataj,Pittaj,Kaphaj,Sannipataj,Raktaj and Sahaj. [3] Ayurveda described some factors for Arsha like cold water, continuous seating and riding suppression of normal urge of micturation and defecation.[4] Arsha can be managed by various parasurgical measures such as Agnikarma, Ksharkarma, Ksharsutra.Acharya Sushruta has advised to apply Ksharasutra in weak,feeble,fearful and difficult to treat patients.[5]
Generally, Snuhi kshira Ksharsutra used for ligation purpose but it also suffers with some adverse effect such as pain, irritation and burning sensation. Therefore, it was required to evaluate efficacy of some other Ksharsutra in the management of Arsha. Shallaki niryasis described as Vranaropaka and Arshoghna
[6] in Dhanvantari nighantu.Considering this fact present study was carried out to measure efficacy of Shallaki niryas Ksharsutra in the management of Arsha. Shallaki Ksharsutra made with water soluble Shallaki niryas liquid instead of Snuhi khira. Shallaki niryas, Apamarga and Haridra were used to prepare Shallaki niryas ksharsutra.
OBJECTIVES
1) To evaluate the effect of Shallaki niryas ksharsutra on sign and symptoms of Arsha.
2) To compare the effect of Shallaki niryas ksharsutra against Snuhi kshira ksharsutra with respect to specific symptoms of Arsha.
MATERIAL AND METHODS
Study Protocol
The present case study was carried out in two diagnosed patients of Arsha. One patient was treated with Shallaki niryas ksharsutra ligation while another patient was treated with Snuhi kshira ksharsutra ligation. Patients were observed on alternate days up to 9 days.
Drug Review
Shallaki, Apamarga and Haridra were used to prepare Shallaki niryas ksharsutra while Snuhi kshira ksharsutra was prepared by using Snuhi kshir, Apamarga and Haridra.
Dr. Amit Mishra (Asst. Professor)
Rasa Shastra & Bhaisajya kalpana
Paper Published in International Journals:-
INTERNATIONAL AYURVEDIC MEDICAL JOURNAL
STUDY ON PHARMACEUTICAL MANUFACTURING OF PANCHAMRITA RASA PREPARED BY DIFFERENT MODIFIED METHODS
Amit Kumar Sharma1, Reetesh Ramnani2, Amit Mishra3
1Associate Scientist, Transformative Learning solutions Gurugram, Haryana, India
2Assistant Prof. Dept. of R.S.& B.K. National Institute of Ayurveda Jaipur, Rajasthan, India
3Assistant prof. Dept. of R.S.& B.K., Vijayshree Ayurved Medical college Jabalpur, Madhya Pradesh, India
Corresponding Author: dr.amitmishra8269@gmail.com
ABSTRACT
Introduction: “Panchamrita Rasa” is a Herbo-mineral formulation mentioned in the management of Shotha, Jalodara, Sannipatik diseases, and Twenty types of Kaphaja Roga, Jwaratisara, Galagraha, Shirasula, etc. Pan- chamrita Rasa is selected for the present study and comes under ‘Khalveeya Rasa yoga Kalpana’. Panchamrita Rasa is also a ‘Sagandha Niragni Murchana’. In Bhaishajya Ratnawali written by Acharya Govind das Sen, ‘Pan- chamrita Rasa has been mentioned under Shotha Chikitsa. There are two other references found in Bhaishajya Ratnawali in Kasa roga and nasa rogadhikar. Method: – In the present study Panchamrita Rasa was prepared by three different methods. The Panchamrita Rasa was prepared in 3 different samples with levigation by water. Sample 1 had Kajjali, Sample 2 had Hingula and sample 3 had Rasasindura as one of the major ingredients. Re- sults: Maximum output was obtained in sample 1. Sample 1 had kajjali as one of the ingredients and Sample 2 had Hingula as one of the ingredients which yielded comparatively less. Conclusion: Here in Panchamrit Rasa each herbal and mineral ingredient is used after proper shodhan procedures. Moreover, it is prepared with three modified methods using Kajjali, Hingula, and Rasa Sindura. For Panchamrita rasa preparation, Kajjali should be preferred over Hingula and Rasasindura as an ingredient.
Keywords: Panchamrita Rasa, Herbomineral, Khalveeya, Bhaishajya Ratnawali, Shotha.
INTRODUCTION
An immense valuable and powerful medicine in the form of metals, minerals & plants is found in nature. But most of the drugs as such are not absorbable into the biological systems until & unless they have cer- tain modifications. The specialized techniques to make these drugs absorbable therapeutically or clini- cally viable is called the pharmaceutical process. It is a clear fact that theory and Practice are two essential aspects of knowledge. A man can’t become perfect with theoretical or practical knowledge alone. Thus, in nutshell, it can be stated that pharmaceutics espe- cially in the field of Ayurveda has one of the supreme importance.
In the present study, Panchamrita Rasa has been pre- pared by three different methods.
Objectives:
The present pharmaceutical study was planned with the following aims & objectives –
To validate the standard method of preparation of
PanchamritaRasa.
To know the difference in PanchamritaRasa pre- pared by three different methodsat pharmaceutical grounds.
Materials: Materials and methods used in this prepa- ration are based on availability, feasibility in the clas- sical indication of Rasashastra, traditional value, and expert opinions.
All the raw materials were procured from the N.I.A. pharmacy.
Methods:
The pharmaceutical was carried out after obtaining permission from the institutional ethics committee (Approval number – IEC/ACA/2015/61) Pharmaceu- tical processes carried out during the study were as follows –
Purification (Shodhana) of raw materials
Kajjali Nirmana.
Rasasindura Nirmana.
Preparation of powders of crude drugs.
Mixing of powders and Kaj- jali/Rasasindura/Hingula.
Preparing Panchamrita Rasa by three different methods.
Pharmaceutical Steps involved
1) Shodhana of Parada
2) Shodhana of Gandhaka
3) Preparation of Kajjali
4) Shodhana of Vatsanabha
5) Shodhana of Tankana
6) Preparation of Fine Powder of Maricha
7) Shodhana of Hingula
8) Preparation of Sama guna Rasasindura
9) Preparation of Panchamrita Rasa
Procedure:
1. Sodhana of Parada:
Shodhana of parada was done as per Rasa Tarangini [1]. 100 g of Parada and 100 g of Sudha churna were taken in the khalwa yantra and Mardana was done for 24 hrs. Then Separation of Parada from Sudha was done with cloth and water. Total Parada ob- tained was 90 g. Loss in this procedure was 10g (10
%). Then 90 g Lashuna paste and 45g Saindhava la- vana were taken and Mardana of Parada was done with it. Mardana was stopped when the color of Kal- ka turned blackish. The separation of Parada from Kalka was done with hot water. In the end, Parada obtained 75g. and 15 g was lost. The total loss of weight of parada was 25 g (25 %).
2. Sodhana of Gandhaka:
Sodhana of Gandhaka was done as per Rasa Ratna Samucchaya [2]. A total of 160 g of Gandhaka was taken. An Iron vessel containing adequate amount of milk (200ml) was taken so that all Gandhaka can be immersed in it and a white thin cloth was covered on its mouth and tied. Coarse powder of Gandhaka was spread on the cloth. Then another stainless-steel ves- sel of equal dimensions was taken. It was put in in- verted position over the first vessel and Sandhi- bandhana was done. Agni was given for ½ hour and allowed for self-cooling. The same process was re- peated three times.
3. Kajjali Preparation:
Kajjali was prepared as per Rasa Tarangini [3]. Sodhi- ta Parada and Suddha Gandhaka were taken in Khalva Yantra and Mardana was started. During trit- uration, a Few drops of water was sprinkled over the
Dr. Sarang Jayprakash Deshpande (Reader)
Rasa Shastra & Bhaisajya kalpana
Paper Published in International Journals:-
1)Preparation and evaluation of Ayurvedic drug Arogyawardhini Tablet, International Journal Of Ayurved and Pharma research, Feb/Apr. 2017, Vol V Issue II
2)Evaluation of efficacy of Herbokam Plus capsules in the patients with stress induced insomnia: A randomized placebo controlled study, International Journal of Drug discovery and Herbal research Oct-Dec 2012, 499-503.
3)Evaluation of safety and efficacy of Herbosol syrup w.r.t. Malnutrition and weight loss in children: Aprospective Clinical trial, Indian journal of herbal technology 2012.
4)A prospective open labeled clinical trial to evaluate safety and efficacy of rheumax capsules in patients of mild to moderate rheumatoid arthritis. Indian journal of herbal technology 2012.
5)An open labeled study to evaluate safety and efficacy of Ugyanetone syrup in menorrhagia. Indian journal of herbal technology 2012.
6)Effect of Polyherbal formulation in patients of PCOS. Journal of pharmacy and biological sciences. Mar-Apr 2013.
7)Multicentric study to Evaluate safety and efficacy of Ugyanetone forte capsules in patients of PCOS. International journal of innovative and applied research. 2015 vol. 3 issue I 32-36
8)Pharmaceutical standardization of Raktpachak vati (Tablet) – A polyherbal formulation,
International journal of Ayurved and pharma research Mar 2017 Vol 5 issue 3
9)Pharmaceutical and Analytical standardization of Raspachak vati (Tablet), International journal of Applied Ayurved research Vol 2 issue 11 Jan-feb 2017.
10)Safety and efficacy of Unex capsules in management of ureteric calculi; A prospective randomized placebo controlled study. International journal of green pharmacy oct- dec 2011.
11)A case report of Urolithiasis of patient with multiple bilateral renal stones, International journal of scientific and research publications, vol 3 issue 6 June 2013.
12)An open labeled study to evaluate safety and efficacy of Unicough syrup in children with acute bronchitis. Journal of Pharmacy and biological sciences, vol 4 issue 5 Nov- Dec 2012.
13)Pharmaceutical and analytical validation of Yograj guggul tablet – A polyherbal Ayurvedic formulation. International Ayurvedic medical journal Apr 2017 5(4).
14)A randomised single blind active controlled, parallel groupstudy comparing the efficacy & safety of the karnim plus® capsules in patients with mild or moderate diabetes mellitus type II. International journal of AYUSH and pharmaceutical sciences Oct 2017, 106- 112.
15)A single blind placebo controlled study to evaluate the efficacy and safety of Herbokam plus capsules (An Ayurvedic formulation) in the patients with stress induced Insomnia. International Ayurvedic Medical Journal, Volume 5, Issue 12, December, 2017.
16)Phrmaceutical standardization and preliminary Physico-chemical profile of Shankha vati (Tablet). International journal of research in Ayurved and pharmacy, Volume 9, Issue 2, Jan 2018.
17)A single blind, randomized, placebo controlled, multicentric study comparing the efficacy & safety of Rheumax capsules in the patients with mild to modarate rheumatoid arthritis; International Journal of Recent Advances in Multidisciplinary Research Vol. 05, Issue 02, pp.3607-3610, February, 2018.
18)An open labled study to evaluate the efficacy and safety of Valiliv® capsules in the patients with viral hepatitis. International Journal of Development Research Vol. 08, Issue, 02, pp.19059-19062, February, 2018
19)Management of lyme disease with a polyherbal combination of ‘out of lyme’ and ‘divine 9 adaptogen’ immunoprotector. International Ayurvedic medical journal Volume 6, Issue 11, November – 2018
20)A Case Discussion On Psoriasis. Aayushi International Interdisciplinary Research Journal, Special Issue No. 78, September – 2020
21)Pharmaceutical and Analytical Standardization of “Mansapachak Vati” Aayushi International Interdisciplinary Research Journal, Special Issue No. 78, September – 2020
Dr. Mamata Tirankar (Reader)
Swasth Vritta & Yoga
Paper Published in International Journals:-
1)To Study the Efficacy of Yastimadhuk Tail PratimarshaNasya In the Management of Khalitya ,International Journal of Ayurvedic Medicine, 2019 ,10 (3), 248-251.
2)Ayurvedic Approach to Care Skin- A Review, International Journal of Current Advanced Research Vol 8, issue 12 (A), pp 20622-20624, December 2019
3)Pharmaceutical and Analytical Study of Yastimadhuk Tail, world Journal of Pharmaceutical Research Vol 8, issue 13, Nov 2019.
Dr. Shrikant Hadole (Asst. Professor)
Dravyaguna Vigyana
Paper Published in International Journals:
1. Clinical assessment of Shankhapushpi (Convolvulus PluricaulisHoisy)
and Aparajita (ClitoriaTernatea Linn) granules in Medhya Karma with
the help of IQ test
2. PHYTOCHEMICAL STUDY OF DARUHARIDRA (BERBERIS ARISTATA DC) AND ITS HEPATOPROTECTIVE
EFFICACY IN INFECTIVE HEPATITIS
3. “CLINICAL EVALUATION OF BIBHITAKI PHALA (TERMINALIA BELLERICA
ROXB.) IN TAMAKA SHVASA (BRONCHIAL ASTHMA)”
4. Concept Of Salutariness In Ayurveda With Specialreference To
Aahar (Food)
5. HEMOSTATIC PROCEDURES BY SUSHRUTA:
A CONTRIBUTION TO PRESENT SURGICAL PRACTICES
6. ORGANIC FARMING – THE SCIENTIFICALLY REDEVELOPED TRADITIONAL
FARMING – A REVIEW
7. RANDOMIZED CONTROLLED CLINICAL STUDY TO EVALUATE ROLE OF
AAMRABEEJA-HARITAKI LEPA in Darunak (Dandruff)
8. COVID-19: AN APPLIED INTERVENTION THROUGH AYURVEDA
Click here…………. COVID-19 IJAPR
Dr. Amit Mishra (Asst. Professor)
Rasa Shastra & Bhaisajya kalpana
Paper Published in International Journals:-
1.)PHARMACEUTICAL STANDARDISATION OF SAMAGUNA BALI JARITA ANTARDHUMA RASASINDURA PREPARED BY MODIFIED METHOD published in IJAPC journal.
2.)EMERGING NEED OF PHARMACOKINETICS IN DEMYSTIFICATION OF HERBO-MINERAL COMPOUNDS published in IJAPR Journal
3.)EXPERIMENTAL STUDIES ON VARIOUS LOHA PREAPARATIONS W.S.R TO “MRITANI LOHANI RASI BHAVANTI” published in IAMJ Journal.
4.)EXPERIMENTAL STUDIES ON HARAGOURIRASA W.S.R TO MRITANI LOHANI RASI BHAVANTI. Published in IJAR
5.)IMPORTANCE OF MEDHYA RASAYANA DRAVYA IN RASAYANA THERAPY published in IAMJ Journal
6.) IMPORTANCE OF CANTILLATION (CHANTING)-A DIVINE REMEDY IN AYURVEDA published in IRJAY
7.)PHARMACOGNOSTICAL AND PHYTOCHEMICAL ANALYSIS OF DRY AND WET GUDUCHI (Tinospora cordifolia Willd.& Miers.ex Hook.F&Thoms.) published in IJAPC.
8.)A CRITICAL REVIEW ON VARIOUS ASPECTS OF “PUSHYANUGA CHURNA”. Accepted in NIA JDR .
9.)“STUDY ON PHARMACEUTICAL MANUFACTURING OF PANCHAMRITA RASA PREPARED BY DIFFERENT MODIFIED METHODS”accepted in journal of ayurveda NIA JAIPUR.